Enzyme Kinetics: Interactive Simulations and Excel Spreadsheets
The simulations run in your browser. You can download the excel spreadsheets and watch the screencasts that help you use them.
Enzyme Inhibition Kinetics

Try to answer these questions before determining the answer with the simulation. We suggest that you write down the reasons for your answers.
- For competitive inhibition in the Lineweaver-Burke equation, how is the y-intercept affected by an increase in inhibitor concentration?
- For the uncompetitive inhibition Lineweaver-Burke equation, how is the y-intercept affected by an increase in inhibitor concentration?
Try to answer these questions before determining the answer with the simulation. We suggest that you write down the reasons for your answers.
- Is the substrate concentration impacted greatly or slightly as the inhibitor concentration increases in a CSTR?
- Is the substrate concentration impacted greatly or slightly as the inhibitor concentration increases in a batch reactor?