LearnChemE

Nonlinear Regression: Example Problems

Try to solve these problems before watching the solutions in the screencasts.

Example Problem 1
Demonstrates how to use POLYMATH to carry out nonlinear regression to fit kinetic data from a differential plug flow reactor. POLYMATH file here.
Example Problem 2

Determine parameters Vmax and Km for Michaelis-Menten enzyme kinetics using Excel Solver. Excel file here.

Example Problem 3

Determine \(R^2\) value and confidence limits for parameters for Michaelis-Menten enzyme kinetics using Excel Solver. Excel file here.

Example Problem 4 (optional)

Demonstrates how to carry out nonlinear regression with Excel to determine the activation energy and pre-exponential factor for a chemical reaction. Rate constants as a function of temperature are used for a second-order reaction.

Determine Activation Energy using Nonlinear Regression with Excel Solver

Excel file here.