Fed-Batch Fermentation

A fermentor is fed at t = 20 h with a sterile substrate. In the absence of outlet flow, the volume in the batch-fed fermentor will increase linearly. This simulation shows the time-dependent behavior of four functions: the biomass concentration, the substrate concentration, the product concentration, and the volume in the reactor. The biomass concentration becomes constant and the product concentration and volume increase linearly because they depend linearly on the biomass and the inlet flow rate, respectively. The total biomass increases linearly versus time. This behavior corresponds to a situation where the growth rate of biomass is limited by the feeding rate.

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Author: Housam Binous. Open content licensed under CC BY-NC-SA.

View the source code for this simulation